Carnitine Insufficiency Caused by Aging and Overnutrition Compromises Mitochondrial Performance and Metabolic Control

In addition to its essential role in permitting mitochondrial import and oxidation of long chain fatty acids, carnitine also functions as an acyl group acceptor that facilitates mitochondrial export of excess carbons in the form of acylcarnitines. Recent evidence suggests carnitine requirements incr...

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Autors principals: Noland, Robert C., Koves, Timothy R., Seiler, Sarah E., Lum, Helen, Lust, Robert M., Ilkayeva, Olga, Stevens, Robert D., Hegardt, Fausto G., Muoio, Deborah M.
Format: Artigo
Idioma:Inglês
Publicat: American Society for Biochemistry and Molecular Biology 2009
Matèries:
Metabolism and Bioenergetics
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC2755692/
https://ncbi.nlm.nih.gov/pubmed/19553674
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M109.032888
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