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A peptidomimetic of NT-3 acts as a TrkC antagonist
Neurotrophins are a family of growth factors that regulate the peripheral and central nervous system. We designed and tested a mini-library of small molecules peptidomimetics based on β-turns of the neurotrophin growth factor polypeptides NT-3, which is the natural ligand for TrkC receptors. Biologi...
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| Main Authors: | , , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2009
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2755609/ https://ncbi.nlm.nih.gov/pubmed/19647025 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.peptides.2009.07.015 |
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