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A peptidomimetic of NT-3 acts as a TrkC antagonist

Neurotrophins are a family of growth factors that regulate the peripheral and central nervous system. We designed and tested a mini-library of small molecules peptidomimetics based on β-turns of the neurotrophin growth factor polypeptides NT-3, which is the natural ligand for TrkC receptors. Biologi...

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Hlavní autoři: Brahimi, Fouad, Malakhov, Andrey, Lee, Hong Boon, Pattarawarapan, Mookda, Ivanisevic, Lubijca, Burgess, Kevin, Saragovi, H. Uri
Médium: Artigo
Jazyk:Inglês
Vydáno: 2009
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On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC2755609/
https://ncbi.nlm.nih.gov/pubmed/19647025
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.peptides.2009.07.015
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