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Bivalent peptidomimetic ligands of TrkC are biased agonists, selectively induce neuritogenesis, or potentiate neurotrophin-3 trophic signals

This study was initiated to find small molecule ligands that would induce a functional response when docked with neurotrophin Trk receptors. “Minimalist” mimics of β-turns were designed for this purpose. These mimics are: (i) rigid, yet easily folded into turn-like conformations, and (ii) readily ac...

पूर्ण विवरण

में बचाया:
ग्रंथसूची विवरण
मुख्य लेखकों: Chen, Dianjun, Brahimi, Fouad, Angell, Yu, Li, Yu-Chin, Moscowicz, Jennifer, Saragovi, H. Uri, Burgess, Kevin
स्वरूप: Artigo
भाषा:Inglês
प्रकाशित: 2009
विषय:
ऑनलाइन पहुंच:https://ncbi.nlm.nih.gov/pmc/articles/PMC2756187/
https://ncbi.nlm.nih.gov/pubmed/19735123
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/cb9001415
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