Bivalent Diketopiperazine-based Tropomysin Receptor Kinase C (TrkC) Antagonists

由 Liu, Jing, Brahimi, Fouad, Saragovi, H. Uri, Burgess, Kevin
出版 2010

Combinatorial Assembly of Small Molecules into Bivalent Antagonists of TrkC or TrkA Receptors

由 Brahimi, Fouad, Ko, Eunhwa, Malakhov, Andrey, Burgess, Kevin, Saragovi, H. Uri
出版 2014

In retinitis pigmentosa TrkC.T1-dependent vectorial Erk activity upregulates glial TNF-α, causing selective neuronal death

由 Galán, Alba, Jmaeff, Sean, Barcelona, Pablo F., Brahimi, Fouad, Sarunic, Marinko V., Saragovi, H. Uri
發表在 Cell Death Dis (2017)

A peptidomimetic of NT-3 acts as a TrkC antagonist

由 Brahimi, Fouad, Malakhov, Andrey, Lee, Hong Boon, Pattarawarapan, Mookda, Ivanisevic, Lubijca, Burgess, Kevin, Saragovi, H. Uri
出版 2009

Bivalent peptidomimetic ligands of TrkC are biased agonists, selectively induce neuritogenesis, or potentiate neurotrophin-3 trophic signals

由 Chen, Dianjun, Brahimi, Fouad, Angell, Yu, Li, Yu-Chin, Moscowicz, Jennifer, Saragovi, H. Uri, Burgess, Kevin
出版 2009

A monovalent agonist of TrkA tyrosine kinase receptors can be converted into a bivalent antagonist

由 Brahimi, Fouad, Liu, Jing, Malakhov, Andrey, Chowdhury, Shafinaz, Purisima, Enrico O., Ivanisevic, Ljubica, Caron, Antoine, Burgess, Kevin, Saragovi, H. Uri
出版 2010

Rapid High-Yield Production of Functional SARS-CoV-2 Receptor Binding Domain by Viral and Non-Viral Transient Expression for Pre-Clinical Evaluation

由 Farnós, Omar, Venereo-Sánchez, Alina, Xu, Xingge, Chan, Cindy, Dash, Shantoshini, Chaabane, Hanan, Sauvageau, Janelle, Brahimi, Fouad, Saragovi, Uri, Leclerc, Denis, Kamen, Amine A.
發表在 Vaccines (Basel) (2020)

Alternative Splicing of a Receptor Intracellular Domain Yields Different Ectodomain Conformations, Enabling Isoform-Selective Functional Ligands

由 Brahimi, Fouad, Galan, Alba, Jmaeff, Sean, Barcelona, Pablo F., De Jay, Nicolas, Dejgaard, Kurt, Young, Jason C., Kleinman, Claudia L., Thomas, David Y., Saragovi, H. Uri
發表在 iScience (2020)

The Paradoxical Signals of Two TrkC Receptor Isoforms Supports a Rationale for Novel Therapeutic Strategies in ALS

由 Brahimi, Fouad, Maira, Mario, Barcelona, Pablo F., Galan, Alba, Aboulkassim, Tahar, Teske, Katrina, Rogers, Mary-Louise, Bertram, Lisa, Wang, Jing, Yousefi, Masoud, Rush, Robert, Fabian, Marc, Cashman, Neil, Saragovi, H. Uri
發表在 PLoS One (2016)