Critical role for ERK1/2 in bone marrow and fetal liver–derived primary megakaryocyte differentiation, motility, and proplatelet formation

OBJECTIVE: Megakaryopoiesis and platelet formation is a multistep process through which hematopoietic progenitor cells develop into mature megakaryocytes (MKs) and form proplatelets. The present study investigates the regulation of different steps of megakaryopoiesis (i.e., differentiation, migratio...

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Main Authors: Mazharian, Alexandra, Watson, Steve P., Séverin, Sonia
Format: Artigo
Jezik:Inglês
Izdano: Elsevier Science Inc 2009
Teme:
Megakaryocytopoiesis
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC2755112/
https://ncbi.nlm.nih.gov/pubmed/19619605
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.exphem.2009.07.006
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