Critical shifts in lipid metabolism promote megakaryocyte differentiation and proplatelet formation

During megakaryopoiesis, megakaryocytes (MK) undergo cellular morphological changes with strong modification of membrane composition and lipid signaling. Here we adopt a lipid-centric multiomics approach to create a quantitative map of the MK lipidome during maturation and proplatelet formation. Dat...

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Detalhes bibliográficos
Publicado no:Nat Cardiovasc Res
Main Authors: de Jonckheere, Bianca, Kollotzek, Ferdinand, Münzer, Patrick, Göb, Vanessa, Fischer, Melina, Mott, Kristina, Coman, Cristina, Troppmair, Nina Nicole, Manke, Mailin-Christin, Zdanyte, Monika, Harm, Tobias, Sigle, Manuel, Kopczynski, Dominik, Bileck, Andrea, Gerner, Christopher, Hoffmann, Nils, Heinzmann, David, Assinger, Alice, Gawaz, Meinrad, Stegner, David, Schulze, Harald, Borst, Oliver, Ahrends, Robert
Formato: Artigo
Idioma:Inglês
Publicado em: 2023
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7615361/
https://ncbi.nlm.nih.gov/pubmed/38075556
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s44161-023-00325-8
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