Identification of key lipids critical for platelet activation by comprehensive analysis of the platelet lipidome

Platelet integrity and function critically depend on lipid composition. However, the lipid inventory in platelets was hitherto not quantified. Here, we examined the lipidome of murine platelets using lipid-category tailored protocols on a quantitative lipidomics platform. We could show that the plat...

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Vydáno v:Blood
Hlavní autoři: Peng, Bing, Geue, Sascha, Coman, Cristina, Münzer, Patrick, Kopczynski, Dominik, Has, Canan, Hoffmann, Nils, Manke, Mailin-Christin, Lang, Florian, Sickmann, Albert, Gawaz, Meinrad, Borst, Oliver, Ahrends, Robert
Médium: Artigo
Jazyk:Inglês
Vydáno: American Society of Hematology 2018
Témata:
Platelets and Thrombopoiesis
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC6137561/
https://ncbi.nlm.nih.gov/pubmed/29784642
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1182/blood-2017-12-822890
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