Identification of key lipids critical for platelet activation by comprehensive analysis of the platelet lipidome

Platelet integrity and function critically depend on lipid composition. However, the lipid inventory in platelets was hitherto not quantified. Here, we examined the lipidome of murine platelets using lipid-category tailored protocols on a quantitative lipidomics platform. We could show that the plat...

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Detalhes bibliográficos
Publicado no:Blood
Main Authors: Peng, Bing, Geue, Sascha, Coman, Cristina, Münzer, Patrick, Kopczynski, Dominik, Has, Canan, Hoffmann, Nils, Manke, Mailin-Christin, Lang, Florian, Sickmann, Albert, Gawaz, Meinrad, Borst, Oliver, Ahrends, Robert
Formato: Artigo
Idioma:Inglês
Publicado em: American Society of Hematology 2018
Assuntos:
Platelets and Thrombopoiesis
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6137561/
https://ncbi.nlm.nih.gov/pubmed/29784642
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1182/blood-2017-12-822890
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