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Proplatelet formation of megakaryocytes is triggered by autocrine-synthesized estradiol

A matured megakaryocyte releases thousands of platelets through a drastic morphological change, proplatelet formation (PPF). The megakaryocyte/erythrocyte-specific transcription factor, p45 NF-E2, is essential for initiating PPF, but the factor regulating PPF has not been identified. Here we report...

Täydet tiedot

Tallennettuna:
Bibliografiset tiedot
Julkaisussa:Genes Dev
Päätekijät: Nagata, Yuka, Yoshikawa, Jun, Hashimoto, Atsushi, Yamamoto, Masayuki, Payne, Anita H., Todokoro, Kazuo
Aineistotyyppi: Artigo
Kieli:Inglês
Julkaistu: Cold Spring Harbor Laboratory Press 2003
Aiheet:
Linkit:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC289146/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/14665668/
https://ncbi.nlm.nih.govhttps://doi.org/10.1101/gad.1128003
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