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Proplatelet formation of megakaryocytes is triggered by autocrine-synthesized estradiol
A matured megakaryocyte releases thousands of platelets through a drastic morphological change, proplatelet formation (PPF). The megakaryocyte/erythrocyte-specific transcription factor, p45 NF-E2, is essential for initiating PPF, but the factor regulating PPF has not been identified. Here we report...
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| Main Authors: | , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Cold Spring Harbor Laboratory Press
2003
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC289146/ https://ncbi.nlm.nih.gov/pubmed/14665668 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1101/gad.1128003 |
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