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Megakaryocyte Polyploidization and Proplatelet Formation in Low-Attachment Conditions

In vitro-derived platelets (PLTs), which could provide an alternative source of PLTs for patient transfusions, are formed from polyploid megakaryocytes (MKs) that extend long cytoplasmic projections, termed proplatelets (proPLTs). In this study, we compared polyploidization and proPLT formation (PPF...

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Detalhes bibliográficos
Publicado no:Biochem Eng J
Main Authors: Schlinker, Alaina C., Duncan, Mark T., DeLuca, Teresa A., Whitehead, David C., Miller, William M.
Formato: Artigo
Idioma:Inglês
Publicado em: 2016
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4827264/
https://ncbi.nlm.nih.gov/pubmed/27087780
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bej.2016.03.001
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