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Megakaryocyte Polyploidization and Proplatelet Formation in Low-Attachment Conditions

In vitro-derived platelets (PLTs), which could provide an alternative source of PLTs for patient transfusions, are formed from polyploid megakaryocytes (MKs) that extend long cytoplasmic projections, termed proplatelets (proPLTs). In this study, we compared polyploidization and proPLT formation (PPF...

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Pubblicato in:Biochem Eng J
Autori principali: Schlinker, Alaina C., Duncan, Mark T., DeLuca, Teresa A., Whitehead, David C., Miller, William M.
Natura: Artigo
Lingua:Inglês
Pubblicazione: 2016
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC4827264/
https://ncbi.nlm.nih.gov/pubmed/27087780
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bej.2016.03.001
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