Imaging of Cyclosporine Inhibition of P-Glycoprotein Activity Using (11)C-Verapamil in the Brain: Studies of Healthy Humans

The multiple-drug resistance (MDR) transporter P-glycoprotein (P-gp) is highly expressed at the human blood–brain barrier (BBB). P-gp actively effluxes a wide variety of drugs from the central nervous system, including anticancer drugs. We have previously demonstrated P-gp activity at the human BBB...

ver descrição completa

Na minha lista:
Detalhes bibliográficos
Main Authors: Muzi, Mark, Mankoff, David A., Link, Jeanne M., Shoner, Steve, Collier, Ann C., Sasongko, Lucy, Unadkat, Jashvant D.
Formato: Artigo
Idioma:Inglês
Publicado em: 2009
Assuntos:
Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2754733/
https://ncbi.nlm.nih.gov/pubmed/19617341
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2967/jnumed.108.059162
Tags: Adicionar Tag
Sem tags, seja o primeiro a adicionar uma tag!

Registos relacionados