Llwytho...

PLD2 has both enzymatic and cell proliferation-inducing capabilities, that are differentially regulated by phosphorylation and dephosphorylation

Phospholipase D2 (PLD2) overexpression in mammalian cells results in cell transformation. We have hypothesized that this is due to an increase of de novo DNA synthesis. We show here that overexpression of PLD2-WT leads to an increased DNA synthesis, as measured by the expression levels of the prolif...

Disgrifiad llawn

Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Prif Awduron: Henkels, Karen M., Short, Stephen, Peng, Hong-Juan, Fulvio, Mauricio Di, Gomez-Cambronero, Julian
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: 2009
Pynciau:
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC2754605/
https://ncbi.nlm.nih.gov/pubmed/19715678
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bbrc.2009.08.109
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