Structural Basis of Interactions between Human Glutamate Carboxypeptidase II and Its Substrate Analogs

Human glutamate carboxypeptidase II (GCPII) is involved in neuronal signal transduction and intestinal folate absorption by means of the hydrolysis of its two natural substrates, N-acetyl-aspartyl-glutamate (NAAG) and folyl-poly-γ-glutamates, respectively. During the past years, tremendous efforts h...

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Détails bibliographiques
Auteurs principaux: Barinka, Cyril, Hlouchova, Klara, Rovenska, Miroslava, Majer, Pavel, Dauter, Miroslawa, Hin, Niyada, Ko, Yao-Sen, Tsukamoto, Takashi, Slusher, Barbara S., Konvalinka, Jan, Lubkowski, Jacek
Format: Artigo
Langue:Inglês
Publié: 2008
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Article
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC2753231/
https://ncbi.nlm.nih.gov/pubmed/18234225
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.jmb.2007.12.066
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