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Structural Basis of Interactions between Human Glutamate Carboxypeptidase II and Its Substrate Analogs
Human glutamate carboxypeptidase II (GCPII) is involved in neuronal signal transduction and intestinal folate absorption by means of the hydrolysis of its two natural substrates, N-acetyl-aspartyl-glutamate (NAAG) and folyl-poly-γ-glutamates, respectively. During the past years, tremendous efforts h...
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| Main Authors: | , , , , , , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado: |
2008
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| Assuntos: | |
| Acceso en liña: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2753231/ https://ncbi.nlm.nih.gov/pubmed/18234225 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.jmb.2007.12.066 |
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