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Structural and Biochemical Characterization of the Folyl-poly-γ-L-glutamate Hydrolyzing Activity of Human Glutamate Carboxypeptidase II
In addition to its well-characterized role in the central nervous system, human glutamate carboxypeptidase II (GCPII, Uniprot ID Q04609) acts as a folate hydrolase in the small intestine, participating in the absorption of dietary polyglutamylated folates (FolGlu(n)), which are the provitamin form o...
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| 發表在: | FEBS J |
|---|---|
| Main Authors: | , , , , , , |
| 格式: | Artigo |
| 語言: | Inglês |
| 出版: |
2014
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| 主題: | |
| 在線閱讀: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6257983/ https://ncbi.nlm.nih.gov/pubmed/24863754 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/febs.12857 |
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