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Structural and Biochemical Characterization of the Folyl-poly-γ-L-glutamate Hydrolyzing Activity of Human Glutamate Carboxypeptidase II

In addition to its well-characterized role in the central nervous system, human glutamate carboxypeptidase II (GCPII, Uniprot ID Q04609) acts as a folate hydrolase in the small intestine, participating in the absorption of dietary polyglutamylated folates (FolGlu(n)), which are the provitamin form o...

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Detalhes bibliográficos
Publicado no:FEBS J
Main Authors: Navrátil, Michal, Ptáček, Jakub, Šácha, Pavel, Starková, Jana, Lubkowski, Jacek, Bařinka, Cyril, Konvalinka, Jan
Formato: Artigo
Idioma:Inglês
Publicado em: 2014
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6257983/
https://ncbi.nlm.nih.gov/pubmed/24863754
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/febs.12857
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