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The type III histone deacetylase Sirt1 is essential for maintenance of T cell tolerance in mice
Although many self-reactive T cells are eliminated by negative selection in the thymus, some of these cells escape into the periphery, where they must be controlled by additional mechanisms. However, the molecular mechanisms underlying peripheral T cell tolerance and its maintenance remain largely u...
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| 主要な著者: | , , , , , , , , , , |
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| フォーマット: | Artigo |
| 言語: | Inglês |
| 出版事項: |
American Society for Clinical Investigation
2009
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| 主題: | |
| オンライン･アクセス: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2752073/ https://ncbi.nlm.nih.gov/pubmed/19729833 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1172/JCI38902 |
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