The type III histone deacetylase Sirt1 is essential for maintenance of T cell tolerance in mice

Although many self-reactive T cells are eliminated by negative selection in the thymus, some of these cells escape into the periphery, where they must be controlled by additional mechanisms. However, the molecular mechanisms underlying peripheral T cell tolerance and its maintenance remain largely u...

Disgrifiad llawn

Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Prif Awduron: Zhang, Jinping, Lee, Sang-Myeong, Shannon, Stephen, Gao, Beixue, Chen, Weimin, Chen, An, Divekar, Rohit, McBurney, Michael W., Braley-Mullen, Helen, Zaghouani, Habib, Fang, Deyu
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: American Society for Clinical Investigation 2009
Pynciau:
Research Article
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC2752073/
https://ncbi.nlm.nih.gov/pubmed/19729833
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1172/JCI38902
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