The type III histone deacetylase Sirt1 is essential for maintenance of T cell tolerance in mice

Although many self-reactive T cells are eliminated by negative selection in the thymus, some of these cells escape into the periphery, where they must be controlled by additional mechanisms. However, the molecular mechanisms underlying peripheral T cell tolerance and its maintenance remain largely u...

Deskribapen osoa

Gorde:
Xehetasun bibliografikoak
Egile Nagusiak: Zhang, Jinping, Lee, Sang-Myeong, Shannon, Stephen, Gao, Beixue, Chen, Weimin, Chen, An, Divekar, Rohit, McBurney, Michael W., Braley-Mullen, Helen, Zaghouani, Habib, Fang, Deyu
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: American Society for Clinical Investigation 2009
Gaiak:
Research Article
Sarrera elektronikoa:https://ncbi.nlm.nih.gov/pmc/articles/PMC2752073/
https://ncbi.nlm.nih.gov/pubmed/19729833
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1172/JCI38902
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