The type III histone deacetylase Sirt1 is essential for maintenance of T cell tolerance in mice

Although many self-reactive T cells are eliminated by negative selection in the thymus, some of these cells escape into the periphery, where they must be controlled by additional mechanisms. However, the molecular mechanisms underlying peripheral T cell tolerance and its maintenance remain largely u...

पूर्ण विवरण

में बचाया:
ग्रंथसूची विवरण
मुख्य लेखकों: Zhang, Jinping, Lee, Sang-Myeong, Shannon, Stephen, Gao, Beixue, Chen, Weimin, Chen, An, Divekar, Rohit, McBurney, Michael W., Braley-Mullen, Helen, Zaghouani, Habib, Fang, Deyu
स्वरूप: Artigo
भाषा:Inglês
प्रकाशित: American Society for Clinical Investigation 2009
विषय:
Research Article
ऑनलाइन पहुंच:https://ncbi.nlm.nih.gov/pmc/articles/PMC2752073/
https://ncbi.nlm.nih.gov/pubmed/19729833
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1172/JCI38902
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