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Heat and mass transfer scale-up issues during freeze drying: II. Control and characterization of the degree of supercooling
This study aims to investigate the effect of the ice nucleation temperature on the primary drying process using an ice fog technique for temperature-controlled nucleation. In order to facilitate scale up of the freeze-drying process, this research seeks to find a correlation of the product resistanc...
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| Autores principales: | , , , |
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| Formato: | Artigo |
| Lenguaje: | Inglês |
| Publicado: |
Springer-Verlag
2004
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| Materias: | |
| Acceso en línea: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2750483/ https://ncbi.nlm.nih.gov/pubmed/15760055 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1208/pt050458 |
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