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Heat and mass transfer scale-up issues during freeze-drying, III: Control and characterization of dryer differences via operational qualification tests

The objective of this research was to estimate differences in heat and mass transfer between freeze dryers due to inherent design characteristics using data obtained from sublimation tests. This study also aimed to provide guidelines for convenient scale-up of the freeze-drying process. Data obtaine...

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Main Authors: Rambhatla, S., Tchessalov, S., Pikal, Michael J.
Formato: Artigo
Idioma:Inglês
Publicado: Springer-Verlag 2006
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC2750289/
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1208/pt070239
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