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Heat and mass transfer scale-up issues during freeze-drying, I: Atypical radiation and the edge vial effect

The aim of this study is to determine whether radiation heat transfer is responsible for the position dependence of heat transfer known as the edge vial effect. Freeze drying was performed on a laboratory-scale freeze dryer using pure water with vials that were fully stoppered but had precision cut...

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Detalhes bibliográficos
Main Authors: Rambhatla, Shailaja, Pikal, Michael J.
Formato: Artigo
Idioma:Inglês
Publicado em: Springer-Verlag 2003
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2750592/
https://ncbi.nlm.nih.gov/pubmed/12916896
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1208/pt040214
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