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Evaluation of manometric temperature measurement (MTM), a process analytical technology tool in freeze drying, part III: Heat and mass transfer measurement

This article evaluates the procedures for determining the vial heat transfer coefficient and the extent of primary drying through manometric temperature measurement (MTM). The vial heat transfer coefficients (K(v)) were calculated from the MTM-determined temperature and resistance and compared with...

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Detalhes bibliográficos
Main Authors: Tang, Xiaolin Charlie, Nail, Steven L., Pikal, Michael J.
Formato: Artigo
Idioma:Inglês
Publicado em: Springer-Verlag 2014
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2750334/
https://ncbi.nlm.nih.gov/pubmed/17285746
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1208/pt070497
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