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Evaluation of manometric temperature measurement, a process analytical technology tool for freeze-drying: Part II measurement of dry-layer resistance

The purpose of this work was to study the factors that may cause systematic errors in the manometric temperature measurement (MTM) procedure used to determine product dry-layer resistance to vapor flow. Product temperature and dry-layer resistance were obtained using MTM software installed on a labo...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Hauptverfasser: Tang, Xiaolin Charlie, Nail, Steven L., Pikal, Michael J.
Format: Artigo
Sprache:Inglês
Veröffentlicht: Springer-Verlag 2014
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2750330/
https://ncbi.nlm.nih.gov/pubmed/17285744
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1208/pt070493
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