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Tryptophan Conformations Associated with Partial Unfolding in Ribonuclease T1
The origin of the biexponential fluorescence decay of Trp in ribonuclease T1 under mildly destabilizing conditions, such as increased pH or temperature, or the presence of detergent, is still not understood. We have performed two extended replica-exchange molecular dynamics simulations to obtain a d...
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| Главные авторы: | , , , , |
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| Формат: | Artigo |
| Язык: | Inglês |
| Опубликовано: |
The Biophysical Society
2009
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| Предметы: | |
| Online-ссылка: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2749795/ https://ncbi.nlm.nih.gov/pubmed/19751684 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bpj.2009.07.015 |
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