Tryptophan Conformations Associated with Partial Unfolding in Ribonuclease T1

The origin of the biexponential fluorescence decay of Trp in ribonuclease T1 under mildly destabilizing conditions, such as increased pH or temperature, or the presence of detergent, is still not understood. We have performed two extended replica-exchange molecular dynamics simulations to obtain a d...

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Sonraí Bibleagrafaíochta
Main Authors: Moors, Samuel L.C., Jonckheer, Abel, De Maeyer, Marc, Engelborghs, Yves, Ceulemans, Arnout
Formáid: Artigo
Teanga:Inglês
Foilsithe: The Biophysical Society 2009
Ábhair:
Protein
Rochtain Ar Líne:https://ncbi.nlm.nih.gov/pmc/articles/PMC2749795/
https://ncbi.nlm.nih.gov/pubmed/19751684
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bpj.2009.07.015
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