Tryptophan Conformations Associated with Partial Unfolding in Ribonuclease T1

The origin of the biexponential fluorescence decay of Trp in ribonuclease T1 under mildly destabilizing conditions, such as increased pH or temperature, or the presence of detergent, is still not understood. We have performed two extended replica-exchange molecular dynamics simulations to obtain a d...

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Hlavní autoři: Moors, Samuel L.C., Jonckheer, Abel, De Maeyer, Marc, Engelborghs, Yves, Ceulemans, Arnout
Médium: Artigo
Jazyk:Inglês
Vydáno: The Biophysical Society 2009
Témata:
Protein
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC2749795/
https://ncbi.nlm.nih.gov/pubmed/19751684
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bpj.2009.07.015
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