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Tryptophan Rotamers as Evidenced by X-Ray, Fluorescence Lifetimes, and Molecular Dynamics Modeling

We investigated the native-state dynamics of the Bacillus caldolyticus cold-shock protein mutant Bc-Csp L66E, using fluorescence and appropriate molecular dynamics methods. Two fluorescence lifetimes were found, the amplitudes of which agree very well with tryptophan rotamer populations, obtained fr...

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Detalhes bibliográficos
Main Authors: Moors, Samuel L. C., Hellings, Mario, De Maeyer, Marc, Engelborghs, Yves, Ceulemans, Arnout
Formato: Artigo
Idioma:Inglês
Publicado em: Biophysical Society 2006
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC1563760/
https://ncbi.nlm.nih.gov/pubmed/16698786
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1529/biophysj.106.085100
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