Tryptophan Conformations Associated with Partial Unfolding in Ribonuclease T1

The origin of the biexponential fluorescence decay of Trp in ribonuclease T1 under mildly destabilizing conditions, such as increased pH or temperature, or the presence of detergent, is still not understood. We have performed two extended replica-exchange molecular dynamics simulations to obtain a d...

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Bibliografske podrobnosti
Main Authors: Moors, Samuel L.C., Jonckheer, Abel, De Maeyer, Marc, Engelborghs, Yves, Ceulemans, Arnout
Format: Artigo
Jezik:Inglês
Izdano: The Biophysical Society 2009
Teme:
Protein
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC2749795/
https://ncbi.nlm.nih.gov/pubmed/19751684
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bpj.2009.07.015
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