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Amyloid Fibril Formation Can Proceed from Different Conformations of a Partially Unfolded Protein

Protein misfolding and aggregation are interconnected processes involved in a wide variety of nonneuropathic, systemic, and neurodegenerative diseases. More generally, if mutations in sequence or changes in environmental conditions lead to partial unfolding of the native state of a protein, it will...

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Detalhes bibliográficos
Main Authors: Calamai, Martino, Chiti, Fabrizio, Dobson, Christopher M.
Formato: Artigo
Idioma:Inglês
Publicado em: Biophysical Society 2005
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC1366985/
https://ncbi.nlm.nih.gov/pubmed/16169975
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1529/biophysj.105.068726
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