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Formation of Amyloid Fibrils In Vitro from Partially Unfolded Intermediates of Human γC-Crystallin
PURPOSE. Mature-onset cataract results from the formation of light-scattering aggregates of lens crystallins. Although oxidative or mutational damage may be a prerequisite, little is known of the initiation or nucleation of these aggregated states. In mice carrying mutations in γ-crystallin genes, a...
में बचाया:
| मुख्य लेखकों: | , , , , , , |
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| स्वरूप: | Artigo |
| भाषा: | Inglês |
| प्रकाशित: |
Association for Research in Vision and Ophthalmology, Inc.
2010
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| विषय: | |
| ऑनलाइन पहुंच: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2868461/ https://ncbi.nlm.nih.gov/pubmed/19684009 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1167/iovs.09-3987 |
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