TRANSFORMING GROWTH FACTOR-BETA 1 (TGF-β1) INDUCES ANGIOGENESIS THROUGH VASCULAR ENDOTHELIAL GROWTH FACTOR (VEGF)-MEDIATED APOPTOSIS

VEGF and TGF-β1 induce angiogenesis but have opposing effects on endothelial cells. VEGF protects endothelial cells from apoptosis; TGF-β1 induces apoptosis. We have previously shown that VEGF / VEGF receptor-2 (VEGFR2) signaling mediates TGF-β1 induction of apoptosis. This finding raised an importa...

Disgrifiad llawn

Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Prif Awduron: Ferrari, Giovanni, Cook, Brandoch D., Terushkin, Vitaly, Pintucci, Giuseppe, Mignatti, Paolo
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: 2009
Pynciau:
Article
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC2749291/
https://ncbi.nlm.nih.gov/pubmed/19180561
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/jcp.21706
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