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TGF-β1 INDUCES REARRANGEMENT OF FLK-1 – VE-CADHERIN – β- CATENIN COMPLEX AT THE ADHERENS JUNCTION THROUGH VEGF-MEDIATED SIGNALING
VEGF and TGF-β1 induce angiogenesis but have opposing effects on vascular endothelial cells: VEGF promotes survival; TGF-β1 induces apoptosis. We have previously shown that TGF-β1 induces endothelial cell apoptosis via up-regulation of VEGF expression and activation of signaling through VEGF recepto...
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| Main Authors: | , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2008
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2588645/ https://ncbi.nlm.nih.gov/pubmed/18980215 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/jcb.21935 |
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