TGF-β1 INDUCES REARRANGEMENT OF FLK-1 – VE-CADHERIN – β- CATENIN COMPLEX AT THE ADHERENS JUNCTION THROUGH VEGF-MEDIATED SIGNALING

VEGF and TGF-β1 induce angiogenesis but have opposing effects on vascular endothelial cells: VEGF promotes survival; TGF-β1 induces apoptosis. We have previously shown that TGF-β1 induces endothelial cell apoptosis via up-regulation of VEGF expression and activation of signaling through VEGF recepto...

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Détails bibliographiques
Auteurs principaux: Cook, Brandoch D., Ferrari, Giovanni, Pintucci, Giuseppe, Mignatti, Paolo
Format: Artigo
Langue:Inglês
Publié: 2008
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Article
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC2588645/
https://ncbi.nlm.nih.gov/pubmed/18980215
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/jcb.21935
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