Loading...

VEGF, a prosurvival factor, acts in concert with TGF-β1 to induce endothelial cell apoptosis

VEGF and TGF-β1 are potent angiogenesis inducers with opposing effects on endothelial cells. TGF-β1 induces apoptosis; VEGF protects endothelial cells from apoptosis. We found that TGF-β1 promotes endothelial cell expression of FGF-2, which up-regulates VEGF synthesis. Inhibition of VEGF signaling t...

Fuld beskrivelse

Na minha lista:
Bibliografiske detaljer
Main Authors: Ferrari, Giovanni, Pintucci, Giuseppe, Seghezzi, Graziano, Hyman, Kevin, Galloway, Aubrey C., Mignatti, Paolo
Format: Artigo
Sprog:Inglês
Udgivet: National Academy of Sciences 2006
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC1859920/
https://ncbi.nlm.nih.gov/pubmed/17088559
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0605556103
Tags: Tilføj Tag
Ingen Tags, Vær først til at tagge denne postø!