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THROMBIN CLEAVES THE HIGH MOLECULAR WEIGHT FORMS OF BASIC FIBROBLAST GROWTH FACTOR-2 (FGF-2): A NOVEL MECHANISM FOR THE CONTROL OF FGF-2 AND THROMBIN ACTIVITY
The fgf-2 gene encodes low molecular weight (LMW, 18 kDa) and high molecular weight (HMW, 22–24 kDa) forms that originate from alternative translation of a single mRNA and exhibit diverse biological functions. HMW FGF-2 inhibits cell migration and induces cell transformation or growth arrest in a ce...
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| Main Authors: | , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2007
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3727294/ https://ncbi.nlm.nih.gov/pubmed/17968311 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/sj.onc.1210899 |
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