TGF-β1 INDUCES ENDOTHELIAL CELL APOPTOSIS BY SHIFTING VEGF ACTIVATION OF p38(MAPK) FROM THE PRO-SURVIVAL p38β TO PRO-APOPTOTIC p38α

Transforming growth factor-beta1 (TGF-β1) and vascular endothelial growth factor (VEGF), both angiogenesis inducers, have opposing effects on vascular endothelial cells. TGF-β1 induces apoptosis; VEGF induces survival. We have previously shown that TGF-β1 induces endothelial cell expression of VEGF,...

ver descrição completa

Na minha lista:
Detalhes bibliográficos
Main Authors: Ferrari, Giovanni, Terushkin, Vitaly, Wolff, Martin J., Zhang, Xiaodong, Valacca, Cristina, Poggio, Paolo, Pintucci, Giuseppe, Mignatti, Paolo
Formato: Artigo
Idioma:Inglês
Publicado em: 2012
Assuntos:
Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3356490/
https://ncbi.nlm.nih.gov/pubmed/22522454
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1158/1541-7786.MCR-11-0507
Tags: Adicionar Tag
Sem tags, seja o primeiro a adicionar uma tag!

Registos relacionados