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Structure of the S5a:K48-linked diubiquitin complex and its interactions with Rpn13
Degradation by the proteasome typically requires substrate ubiquitination. Two ubiquitin receptors exist in the proteasome, S5a/Rpn10 and Rpn13. Whereas Rpn13 has only one ubiquitin-binding surface, S5a binds ubiquitin with two independent ubiquitin interacting motifs (UIMs). Here, we use NMR and an...
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| Main Authors: | , , , , , , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2009
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2748877/ https://ncbi.nlm.nih.gov/pubmed/19683493 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.molcel.2009.06.010 |
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