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Temporal induction pattern of STAT4 target genes defines potential for Th1 lineage-specific programming

The Signal Transducer and Activator of Transcription factor STAT4 is a critical component in the development of inflammatory adaptive immune responses. It has been extensively characterized as a lineage-determining factor in Th1 development. However, the genetic program activated by STAT4 that resul...

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Autori principali: Good, Seth R., Thieu, Vivian T, Mathur, Anubhav N., Yu, Qing, Stritesky, Gretta L, Yeh, Norman, O'Malley, John T., Perumal, Narayanan B., Kaplan, Mark H.
Natura: Artigo
Lingua:Inglês
Pubblicazione: 2009
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC2748807/
https://ncbi.nlm.nih.gov/pubmed/19710469
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4049/jimmunol.0901411
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