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Stat4 is required for T-bet to promote IL-12-dependent Th1 fate determination
Transcriptional regulatory networks direct the development of specialized cell types. The transcription factors Stat4 and T-bet are required for the development of T helper 1 cells, although the hierarchy of activity by these factors has not been clearly defined. In this report we show that these fa...
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| Главные авторы: | , , , , , , |
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| Формат: | Artigo |
| Язык: | Inglês |
| Опубликовано: |
2008
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| Предметы: | |
| Online-ссылка: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2768040/ https://ncbi.nlm.nih.gov/pubmed/18993086 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.immuni.2008.08.017 |
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