Signal transducer and activator of transcription 4 limits the development of adaptive regulatory T cells

T-cell responses to a cytokine milieu instruct the development of multiple effector phenotypes. While transforming growth factor-β(1) (TGF-β(1)) inhibits the development of T helper type 1 (Th1) and Th2 cells, we demonstrate that like interleukin-6 (IL-6) and IL-4, IL-12 can inhibit the development...

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Main Authors: O’Malley, John T, Sehra, Sarita, Thieu, Vivian T, Yu, Qing, Chang, Hua-Chen, Stritesky, Gretta L, Nguyen, Evelyn T, Mathur, Anubhav N, Levy, David E, Kaplan, Mark H
格式: Artigo
語言:Inglês
出版: Blackwell Science Inc 2009
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Original Articles
在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC2729536/
https://ncbi.nlm.nih.gov/pubmed/19604309
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/j.1365-2567.2008.03037.x
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