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Stat4 Isoforms Differentially Regulate Inflammation and Demyelination in Experimental Allergic Encephalomyelitis

Experimental allergic encephalomyelitis (EAE) is a T cell-mediated autoimmune disease model of multiple sclerosis (MS). Signal transducer and activator of transcription 4 (Stat4) is a transcription factor activated by interleukin 12 (IL-12) and IL-23, two cytokines known to play important roles in t...

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Detalhes bibliográficos
Main Authors: Mo, Caiqing, Chearwae, Wanida, O’Malley, John T., Adams, Suzanne M., Kanakasabai, Saravanan, Walline, Crystal C., Stritesky, Gretta L., Good, Seth R., Perumal, Narayanan B., Kaplan, Mark H., Bright, John J.
Formato: Artigo
Idioma:Inglês
Publicado em: 2008
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2581484/
https://ncbi.nlm.nih.gov/pubmed/18832727
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