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IL-23 promotes maintenance but not commitment to the Th17 lineage

IL-23 plays a critical role establishing inflammatory immunity and enhancing IL-17 production in vivo. However, an understanding of how it performs those functions has been elusive. In this report, using an IL-17-capture technique, we demonstrate that IL-23 maintains the IL-17-secreting phenotype of...

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Detalhes bibliográficos
Main Authors: Stritesky, Gretta L, Yeh, Norman, Kaplan, Mark H.
Formato: Artigo
Idioma:Inglês
Publicado em: 2008
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2678905/
https://ncbi.nlm.nih.gov/pubmed/18941183
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