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In Vitro Enzymatic Characterization of Near Full Length EGFR in Activated and Inhibited States
The epidermal growth factor receptor (EGFR) is a single-pass transmembrane protein with an extracellular ligand-binding region and a cytoplasmic tyrosine kinase. Ligand binding activates the tyrosine kinase, which in turn initiates signaling cascades that influence cell proliferation and differentia...
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| Glavni autori: | , , , , , , , |
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| Format: | Artigo |
| Jezik: | Inglês |
| Izdano: |
2009
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| Teme: | |
| Online pristup: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2747374/ https://ncbi.nlm.nih.gov/pubmed/19518076 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/bi900755n |
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