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RhoA downstream of G(q) and G(12/13) Pathways regulates Protease-activated Receptor-mediated dense granule release in platelets

Platelet secretion is an important physiological event in hemostasis. The protease activated receptors, PAR 1 and PAR 4, and the thromboxane receptor activate the G(12/13) pathways, in addition to the G(q) pathways. Here, we investigated the contribution of G(12/13) pathways to platelet dense granul...

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Detalhes bibliográficos
Main Authors: Jin, Jianguo, Mao, Yingying, Thomas, Dafydd, Kim, Soochong, Daniel, James L., Kunapuli, Satya P.
Formato: Artigo
Idioma:Inglês
Publicado em: 2008
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2745276/
https://ncbi.nlm.nih.gov/pubmed/19073150
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bcp.2008.11.017
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