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Trypsin causes platelet activation independently of known protease-activated receptors

To identify a physiological agonist of PAR3, we used PAR4 null murine platelets, which were known to express only PAR3. In this study, we tested several proteases and found that trypsin, but not heat-inactivated trypsin, activated PAR4 null murine platelets. Even at high concentrations, trypsin caus...

पूर्ण विवरण

में बचाया:
ग्रंथसूची विवरण
मुख्य लेखकों: Mao, Yingying, Kunapuli, Satya P.
स्वरूप: Artigo
भाषा:Inglês
प्रकाशित: 2013
विषय:
ऑनलाइन पहुंच:https://ncbi.nlm.nih.gov/pmc/articles/PMC4077195/
https://ncbi.nlm.nih.gov/pubmed/24030758
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1160/TH13-03-0189
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