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Characterization of a New Peptide Agonist of the Protease-activated Receptor-1

A new peptide (TFRRRLSRATR), from the c-terminal of human platelet P2Y(1) receptor, was synthesized and its biological function was evaluated. This peptide activated platelets in a concentration-dependent manner, causing shape change, aggregation, secretion and calcium mobilization. Of the several r...

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Bibliografiske detaljer
Main Authors: Mao, Yingying, Jin, Jianguo, Kunapuli, Satya P.
Format: Artigo
Sprog:Inglês
Udgivet: 2007
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2246054/
https://ncbi.nlm.nih.gov/pubmed/17950254
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bcp.2007.09.002
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