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Characterization of a New Peptide Agonist of the Protease-activated Receptor-1
A new peptide (TFRRRLSRATR), from the c-terminal of human platelet P2Y(1) receptor, was synthesized and its biological function was evaluated. This peptide activated platelets in a concentration-dependent manner, causing shape change, aggregation, secretion and calcium mobilization. Of the several r...
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| Main Authors: | , , |
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| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
2007
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| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2246054/ https://ncbi.nlm.nih.gov/pubmed/17950254 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bcp.2007.09.002 |
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