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Mutational analysis of residues important for ligand interaction with the human P2Y(12) receptor
The P2Y(12) receptor, a Gi protein-coupled receptor, plays a central role in platelet activation. In this study, we did a mutational analysis of residues possibly involved in the ligand interactions with the human P2Y(12) receptor. Mutant receptors were stably expressed in CHO-K1 cells with an HA-ta...
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| Main Authors: | , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2010
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2948851/ https://ncbi.nlm.nih.gov/pubmed/20599922 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.ejphar.2010.06.023 |
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