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Negative Regulation of G(q)-mediated Pathways in Platelets by G(12/13) Pathways through Fyn Kinase

Platelets contain high levels of Src family kinases (SFKs), but their functional role downstream of G protein pathways has not been completely understood. We found that platelet shape change induced by selective G(12/13) stimulation was potentiated by SFK inhibitors, which was abolished by intracell...

Πλήρης περιγραφή

Αποθηκεύτηκε σε:
Λεπτομέρειες βιβλιογραφικής εγγραφής
Κύριοι συγγραφείς: Kim, Soochong, Kunapuli, Satya P.
Μορφή: Artigo
Γλώσσα:Inglês
Έκδοση: American Society for Biochemistry and Molecular Biology 2011
Θέματα:
Διαθέσιμο Online:https://ncbi.nlm.nih.gov/pmc/articles/PMC3129198/
https://ncbi.nlm.nih.gov/pubmed/21592972
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M110.212274
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