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Negative Regulation of G(q)-mediated Pathways in Platelets by G(12/13) Pathways through Fyn Kinase
Platelets contain high levels of Src family kinases (SFKs), but their functional role downstream of G protein pathways has not been completely understood. We found that platelet shape change induced by selective G(12/13) stimulation was potentiated by SFK inhibitors, which was abolished by intracell...
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| Autors principals: | , |
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| Format: | Artigo |
| Idioma: | Inglês |
| Publicat: |
American Society for Biochemistry and Molecular Biology
2011
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| Matèries: | |
| Accés en línia: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3129198/ https://ncbi.nlm.nih.gov/pubmed/21592972 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M110.212274 |
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