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Targeting of the protein interaction site between FAK and IGF-1R
The interaction of focal adhesion kinase (FAK) and insulin-like growth factor-1 receptor (IGF-1R) plays an important role in cancer cell survival. Targeting this interaction with small molecule drugs could be a novel strategy in cancer therapy. By a series of pull-down assay using GST-tagged FAK fra...
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| Main Authors: | , , , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado: |
2009
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| Assuntos: | |
| Acceso en liña: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2742998/ https://ncbi.nlm.nih.gov/pubmed/19664602 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bbrc.2009.07.156 |
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