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Molecular Requirements for Recognition of Brain Voltage-gated Sodium Channels by Scorpion α-Toxins
The scorpion α-toxin Lqh2 (from Leiurus quinquestriatus hebraeus) is active at various mammalian voltage-gated sodium channels (Na(v)s) and is inactive at insect Na(v)s. To resolve the molecular basis of this preference we used the following strategy: 1) Lqh2 was expressed in recombinant form and ke...
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| Autors principals: | , , , , , , , |
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| Format: | Artigo |
| Idioma: | Inglês |
| Publicat: |
American Society for Biochemistry and Molecular Biology
2009
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| Matèries: | |
| Accés en línia: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2742833/ https://ncbi.nlm.nih.gov/pubmed/19509294 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M109.021303 |
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