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Elucidation of the Molecular Basis of Selective Recognition Uncovers the Interaction Site for the Core Domain of Scorpion α-Toxins on Sodium Channels

Neurotoxin receptor site-3 at voltage-gated Na(+) channels is recognized by various peptide toxin inhibitors of channel inactivation. Despite extensive studies of the effects of these toxins, their mode of interaction with the channel remained to be described at the molecular level. To identify chan...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Hauptverfasser: Gur, Maya, Kahn, Roy, Karbat, Izhar, Regev, Noa, Wang, Jinti, Catterall, William A., Gordon, Dalia, Gurevitz, Michael
Format: Artigo
Sprache:Inglês
Veröffentlicht: American Society for Biochemistry and Molecular Biology 2011
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3186375/
https://ncbi.nlm.nih.gov/pubmed/21832067
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M111.259507
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