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Enzymes in the NAD(+) Salvage Pathway Regulate SIRT1 Activity at Target Gene Promoters
In mammals, nic o tin a mide phosphoribosyltransferase (NAMPT) and nic o tin a mide mononucleotide ad en y lyltransferase 1 (NMNAT-1) constitute a nuclear NAD(+) salvage pathway which regulates the functions of NAD(+)-de pend ent enzymes such as the protein deacetylase SIRT1. One of the major functi...
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| Asıl Yazarlar: | , , , , , , , , |
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| Materyal Türü: | Artigo |
| Dil: | Inglês |
| Baskı/Yayın Bilgisi: |
American Society for Biochemistry and Molecular Biology
2009
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| Konular: | |
| Online Erişim: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2740465/ https://ncbi.nlm.nih.gov/pubmed/19478080 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M109.016469 |
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